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Snapshot · Mar 5
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Details
Acyclovir (Zovirax)
Antiviral
INDICATIONS AND USAGE Herpes Zoster Infections : Acyclovir is indicated for the acute treatment of herpes zoster (shingles). Genital Herpes : Acyclovir is indicated for the treatment of initial episodes and the management of recurrent episodes of genital herpes.
Dose
DOSAGE AND ADMINISTRATION Acute Treatment of Herpes Zoster : 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. Genital Herpes : Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days.
Renal
Special Populations: Adults with Impaired Renal Function: The half-life and total body clearance of acyclovir are dependent on renal function.
Monitoring
WARNINGS Acyclovir capsules are intended for oral ingestion only. Renal failure, in some cases resulting in death, has been observed with acyclovir therapy (see ADVERSE REACTIONS: Observed During Clinical Practice and OVERDOSAGE ).
Pearls
- Patients should be advised to maintain adequate hydration.
- Herpes Zoster : There are no data on treatment initiated more than 72 hours after onset of the zoster rash.
- Patients should be advised to initiate treatment as soon as possible after a diagnosis of herpes zoster.
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